When your friend becomes agitated, specifically in the late afternoon and evening, it is known as sundowning. They may become suspicious, upset or disorientated, see or hear things that are not there and believe things that are not true.
Example: After a short visit, Hannah struggles to maintain a conversation with her daughter. She becomes upset, paces in her room and says “I want to get out of here NOW”. Her daughter notes that her mom experienced similar distress yesterday and the day before around 4:30pm, as she arrives for a visit after work.