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  • Observational Study
    Elisabeth Bruyère Hospital 43 Bruyère Street Ottawa, ON

    Precision Microbiome Nutrition to Improve Brain Health

    What is this Study about?

    The study is aiming to assess whether nutritional intervention with personalized, preselected prebiotics can affect cognitive function in those with Alzheimer’s disease. This study is placebo-controlled, and participants will be randomized to either the placebo or prebiotic.

    Eligibility Criteria

    • Aged 60 or older
    • Diagnosis of Mild Cognitive Impairment, Alzheimer’s disease, or Amnestic Mild Cognitive Impairment
    • Has someone who can be their study partner

    Recruitment End Date

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  • Observational Study
    In-Person

    SCREEN: Measuring nutrition risk in community-living seniors

    What is this Study about?

    We want to determine if a nutrition questionnaire (SCREEN) works well to identify nutrition challenges for older adults with diagnosed memory problems, cognitive impairment or dementia when completed by themselves, or by a care partner on behalf of their cared for person.

    Eligibility Criteria

    You may be eligible if you are:

    • 55 years or older

    • Read/speak English

    • Live within 45km of Waterloo, Guelph or London.

    AND are an:

    • Older adult with diagnosed memory problems, cognitive impairment or dementia with a care partner who either lives with you, or who is in daily contact with you and would be able to support reporting of their eating behaviours

    • If living in a retirement home, the older adult must have lived in their home for at least 3 months and receive 2 or more meals each day from their retirement home

    Recruitment End Date

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  • Clinical Trial
    Alberta, British Columbia & Ontario

    A Trial of the Safety, Tolerability, and Pharmacodynamics of CVL-871 in Subjects With Dementia-Related Apathy

    What is this Study about?

    The purpose of this phase 2 study is to determine whether CVL-871 is safe and tolerable in patients with Dementia-Related Apathy and if CVL-871 shows changes in clinical measurements of apathy. 

    Eligibility Criteria

    • 50-85 years old
    • Diagnosis of apathy
    • Diagnosis of mild to moderate dementia related to Alzheimer's disease, Frontotemporal dementia, Vascular dementia or Lewy Body Disease dementia).

    Recruitment End Date

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