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  • Observational Study
    Online

    What is this Study about?

    This study examines how Black family caregivers in the Greater Toronto Area experience and access social support while caring for a relative living with dementia. Using Straussian Grounded Theory informed by Critical Theory and Intersectionality, the research explores how factors such as race, culture, gender, and community shape caregiving experiences and support-seeking behaviours. Findings will be used to develop theory grounded in the lived experiences of Black caregivers, and to inform more culturally responsive dementia care policies, services, and supports across Canada. This study has been approved by the York University Research Ethics Board (Protocol 130, April 2026).

    Eligibility Criteria

    You are eligible to participate if you:

    • self-identify as Black (for example, African, Caribbean, Black Canadian, Afro-Latin, or another Black identity)
    • are 18 years of age or older
    • live in the Greater Toronto Area
    • provide unpaid care to a family member living with dementia
    • can speak and understand English well enough to take part in an interview

    Recruitment End Date

  • Observational Study
    In-Person

    What is this Study about?

    Votre mémoire vous inquiète? Le laboratoire des neurosciences de la parole et de l'audition de l'Université Laval vous invite à participer à un projet de recherche visant à comprendre la relation entre la cognition, l'audition et ladifficulté de perception de la parole dans le bruit au cours du vieillissement. La participation implique un maximum de 3 visites au Centre de recherche CERVO. La compensation totale pour l’étude est de 150$. Un résumé écrit devotre fonctionnement cognitif vous sera remis à la fin de votre participation

    Eligibility Criteria

    Les critères de base pour participer sont :

    - Être âgé de 50 ans et +

    - Avoir le français québécois comme langue principale

    - Être droitier

    - Avoir des inquiétudes concernant le fonctionnement de sa mémoir

    Recruitment End Date

  • Observational Study
    In-Person

    What is this Study about?

    This study investigates whether digital activity data collected from wearable and mobile devices can be used to understand changes in cognitive functioning associated with aging and neurological conditions. Participants’ daily movement patterns and activity behaviors will be monitored using advanced tracking technology that collects detailed spatial and temporal data. Researchers will analyze these patterns using computational methods to identify digital markers associated with cognitive functioning. 

    Eligibility Criteria

    You are eligible to participate if you are 60 years or older, have a confirmed diagnosis of Alzheimer’s disease, remain relatively independent in your day-to-day life, are able and willing to wear digital activity tracking technology to monitor daily activity patterns, and are able to provide informed consent and participate in study procedures. You are also eligible to participate if you are a partner/caregiver as a healthy control. 

    Recruitment End Date

  • Observational Study
    In-Person

    What is this Study about?

    Compass-ND is a research study designed to assess individuals with different sorts of cognitive and movement changes seen in older adults. We will look at the usefulness of imaging studies, clinical assessments and biomarker tests, together with measurements of memory, thinking and daily functioning, for distinguishing these changes from each other and from healthy aging.

    Eligibility Criteria

    - are between the ages 60-90

    - have up to grade 12 education

    - have an individual (spouse, friend, or relative), called a “study partner,” who is willing to:

    - Accompany you to the study visits

    - Communicate to the study staff of changes in your health status over the period of this study

    Recruitment End Date

  • Observational Study
    Online

    What is this Study about?

    This study explores the experiences of family and friends of long-term care residents. It focuses on how they experience stress, burden, and mental health challenges, and how a single-session online Acceptance and Commitment Therapy (ACT) or educational materials may help. We will use the information gathered from questionnaires and interventions to understand the effectiveness of these supports and to develop recommendations for improving resources, strategies, and interventions to better meet the needs of family and friends, helping them manage stress and maintain wellbeing while caring for someone in long-term care.

    Eligibility Criteria

    You are eligible to participate if you:

    - are at least 18 years old

    - currently reside in Canada

    - have a family member or friend who currently lives in long-term care

    - are not currently receiving psychological treatment

    Recruitment End Date

  • Observational Study
    In-Person

    What is this Study about?

    Thinking skills (also known as cognitive functions), change from younger to older adulthood. In this study we are investigating how these shifting architectures of cognition and brain function relate to one another, and how these brain and cognitive changes impact decision-making in younger and older adults.

    You may qualify to participate if you are: 1) 60 years of age or older, 2) right-handed, 3) in good health, 4) and have normal or corrected-to-normal vision. Participation will involve completing cognitive tasks, questionnaires, and non-invasive brain measurements using MRI. If you are interested in participating in this study, please contact [email protected]

    Eligibility Criteria

    You are eligible to participate if you:

    - Are aged 60 years or older

    - Are right-handed

    - Are cognitively healthy

    - Are able to come in-person to our site, located at the Montreal Neurological Institute

    - Have no metal in your body (e.g., pacemaker, metal plates, orthopedic devices, etc.)

    - Speak English or French

    Recruitment End Date

  • Observational Study
    Online

    What is this Study about?

    CAN-PROTECT is a Canada-wide online study recruiting participants and caregivers of persons with dementia to explore how lifestyle, background, and caretaking factors affect our health, quality of life, cognition, behaviour, and function as we age. CAN-PROTECT data will be analyzed and jointly published by the University of Calgary in partnership with the University of Exeter.

    Eligibility Criteria

    - Age 18 years or older

    - Reside in Canada

    - Have access to a computer/touchscreen device

    - Can provide informed consent

    - Do not have a diagnosis of dementia

    - Additionally, we are enrolling participants who have previously or currently care for persons with dementia for caregiver-specific assessments

    - Ability to speak English

    Recruitment End Date

  • Observational Study
    In-Person

    What is this Study about?

    Our study titled "Investigating the Role of Quantitative Susceptibility Mapping and Oxygen Extraction Fraction as Advanced Neuroimaging Biomarkers in Alzheimer's Disease" aims to develop non-invasive diagnostic biomarkers for Alzheimer's Disease (AD). We focus on evaluating the potential of QSM and OEF to differentiate between AD, Mild Cognitive Impairment (MCI), and Cognitively Unimpaired populations and to predict amyloid and tau pathology, using a Systems Biology approach. Leveraging the McGill University's TRIAD cohort, the study utilizes advanced imaging and machine learning to predict amyloid and tau presence, which could transform AD diagnostics and treatment. Methodologically, it involves preprocessing neuroimaging data and employing machine learning classifiers to analyze these features. The anticipated outcomes include validating QSM and OEF as non-invasive biomarkers for AD, establishing their correlation with amyloid and tau proteins, and developing predictive models for clinical decision-making, potentially resulting in significant advancements in AD diagnostics.

    Eligibility Criteria

    Are a member of the TRIAD cohort at McGill University, falling within one of the following categories: young control, cognitively unimpaired, mild cognitive impairment, or Alzheimer's Disease.

    Are willing and able to undergo advanced neuroimaging techniques including MRI and PET without contraindications.

    Have not had any significant neurological conditions (other than AD for the AD group) that might interfere with the results of the study.

    Have no metal implants, devices, or other conditions that may contraindicate or distort MRI imaging.

    Are not currently participating in other clinical trials or studies that involve interventions which might interfere with the results of this study.

    Are able and willing to provide informed consent for participation in the study or have a legally authorized representative who can do so.

    Do not have a history of substance abuse or other conditions that might confound the imaging and cognitive data.

    Have not undergone any significant head trauma or surgery in the past 6 months.

    Are not pregnant or planning to become pregnant during the duration of the study.

    Are willing to comply with all study-related procedures, imaging sessions, and follow-up evaluations.

    Ability to speak English and French

    Recruitment End Date

  • Observational Study
    In-Person

    What is this Study about?

    The aim of our study is to better understand whether certain lifestyle factors (such as physical activity and hearing) are related to early changes in memory and thinking abilities in older adults. We are especially interested in enrolling individuals who are South Asian or East Asian, because little research has focused on brain health in Canadians of diverse racial/ethnic backgrounds.

    By participating, you will help us better understand how lifestyle factors are related to memory and thinking changes in adults from diverse communities. We hope that this will lead to improved prevention and early intervention strategies for dementia.

    Eligibility Criteria

    You are eligible to participate if you…

    - Are 55-85 years old

    - Have no major medical or psychiatric diagnoses

    - Are comfortable speaking and reading English

    - Are able to undergo an MRI scan

    -Speak English

    Eligibility is dependent on an additional conversation with the study team.

    Recruitment End Date