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  • Observational Study

    What is this Study about?

    Surveying opinions on how to improve diversity in dementia research.

    Eligibility Criteria

    You are eligible to participate if you are:

    1) Involved in dementia research or services

    AND / OR

    2) from an underserved group* in dementia research.

    3)Aged 19 +

    3)Able to complete the web-based survey in one of the following languages: English, French, Chinese (simplified), Punjabi, Inuktitut.

    *Underserved groups in dementia research include: Racial/ethnic minorities (i.e., South Asian, Chinese, Black, Filipino, Arab, Latin American, Southeast Asian, West Asian, Korean, Japanese, or other racial/ethnic minority) Indigenous populations (i.e., First Nations, Inuit, Métis, or other Indigenous group), Sexual/gender minorities (i.e., the LGBTQ2S+ community), Individuals living in rural and/or remote communities, Individuals living with a disability, Individuals with low social and economic conditions.

    Recruitment End Date

  • Observational Study

    What is this Study about?

    Our study titled "Investigating the Role of Quantitative Susceptibility Mapping and Oxygen Extraction Fraction as Advanced Neuroimaging Biomarkers in Alzheimer's Disease" aims to develop non-invasive diagnostic biomarkers for Alzheimer's Disease (AD). We focus on evaluating the potential of QSM and OEF to differentiate between AD, Mild Cognitive Impairment (MCI), and Cognitively Unimpaired populations and to predict amyloid and tau pathology, using a Systems Biology approach. Leveraging the McGill University's TRIAD cohort, the study utilizes advanced imaging and machine learning to predict amyloid and tau presence, which could transform AD diagnostics and treatment. Methodologically, it involves preprocessing neuroimaging data and employing machine learning classifiers to analyze these features. The anticipated outcomes include validating QSM and OEF as non-invasive biomarkers for AD, establishing their correlation with amyloid and tau proteins, and developing predictive models for clinical decision-making, potentially resulting in significant advancements in AD diagnostics.

    Eligibility Criteria

    Are a member of the TRIAD cohort at McGill University, falling within one of the following categories: young control, cognitively unimpaired, mild cognitive impairment, or Alzheimer's Disease.

    Are willing and able to undergo advanced neuroimaging techniques including MRI and PET without contraindications.

    Have not had any significant neurological conditions (other than AD for the AD group) that might interfere with the results of the study.

    Have no metal implants, devices, or other conditions that may contraindicate or distort MRI imaging.

    Are not currently participating in other clinical trials or studies that involve interventions which might interfere with the results of this study.

    Are able and willing to provide informed consent for participation in the study or have a legally authorized representative who can do so.

    Do not have a history of substance abuse or other conditions that might confound the imaging and cognitive data.

    Have not undergone any significant head trauma or surgery in the past 6 months.

    Are not pregnant or planning to become pregnant during the duration of the study.

    Are willing to comply with all study-related procedures, imaging sessions, and follow-up evaluations.

    Ability to speak English and French

    Recruitment End Date

  • Observational Study

    What is this Study about?

    Our overall goal is to improve the surgical experience for older adults with cognitive decline, including people with Alzheimer's and related dementias, their families, and caregivers.

    The aim of this study is to understand and describe the experiences of patients, families, and healthcare providers with postoperative delirium (delirium after surgery), and to identify strategies to support patient and family centered care for patients with postoperative delirium. We will conduct interviews with patients, families, and healthcare providers to describe their experiences with postoperative delirium.

    Our findings will be used to inform the development of a strategy for reducing delirium after surgery.

    Eligibility Criteria

    1) are a patient aged over 65 years who has experienced postoperative delirium (delirium after surgery), or

    2) are a caregiver/family member of a person who has experienced postoperative delirium (delirium after surgery)

    Ability to speak English

    Recruitment End Date

  • Observational Study

    What is this Study about?

    Older adults with normal cognition, mild impairments, and mild dementia can benefit from physical activity. This may be due to factors such as cognitive impairments (memory related), hearing and vision impairments, social factors (stigma, gender) and biological factors (cardiovascular disease, diabetes...etc). But we are not sure how these factors interact to impact physical activity. Therefore, the purpose of this study is to understand the interactions of these factors and thereby increase physical activity participation in older adult populations.

    Eligibility Criteria

    -Older adults (65+)

    -Able to complete the on-line questionnaires (we accept that this will limit participants to mild dementia)

    - Has access to headphones (either in ear or over ear)

    - Ability to speak English

    Recruitment End Date

  • Observational Study
    Online & In-Person

    What is this Study about?

    This study explores the experiences of people with a stroke-related communication disability in financial environments such as banks, potential challenges regarding participation in financial environments, and looks for strategies to enhance their financial inclusion.

    This study will allow adults with post-stroke communication impairments to have a voice to talk about their problems and challenges in financial environments and will provide them with strategies to enhance their financial inclusion, independence, and quality of life.

    Eligibility Criteria

    • Live with stroke-related speech or communication disability,

    • Have done financial activities or have been in financial places after your stroke,

    • Live in Manitoba,

    • Are 18 years old or more,

    • Are interested in taking part in this study,

    • Agree to be audio or video recorded during the study interview.

    Recruitment End Date

  • Observational Study
    Online & In-Person

    What is this Study about?

    This study, "Stranger than Family: Decision-Making & Ethics of Substitution for People Living With

    Dementia Going It Alone", explores how people facing dementia alone are connected with a substitute

    decision-maker and how ideas about capacity, consent, and decision-making affect them.

    Interviews will be conducted with:

    - People who are facing dementia alone

    - Healthcare and social service workers

    - Substitute decision-makers for others who are not close family members or close friends

    The overall goal of this study is to identify opportunities for advocacy, policy, and practice change to

    better support people facing dementia alone.

    Eligibility Criteria

    You are eligible to participate if you:

    - Live in Ontario or Alberta AND

    - Have a diagnosis of dementia or are at-risk and planning for a future living with dementia and are

    facing dementia alone OR

    - Are a healthcare or social service worker, or other professional who has experience trying to connect

    adult clients with a substitute decision-maker OR

    - Have experience as a substitute decision-maker for someone living with dementia who is not a close

    family member or friend

    In addition, to be eligible you must:

    - Be able to participate in an interview over the phone, on Zoom, or in-person AND

    - Understand the purpose of the study and what participation involves

    -Speak English

    Recruitment End Date