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  • Observational Study
    Online & In-Person

    Decision-Making & Ethics of Substitution for People Living With Dementia Going It Alone

    What is this Study about?

    This study, "Stranger than Family: Decision-Making & Ethics of Substitution for People Living With

    Dementia Going It Alone", explores how people facing dementia alone are connected with a substitute

    decision-maker and how ideas about capacity, consent, and decision-making affect them.

    Interviews will be conducted with:

    - People who are facing dementia alone

    - Healthcare and social service workers

    - Substitute decision-makers for others who are not close family members or close friends

    The overall goal of this study is to identify opportunities for advocacy, policy, and practice change to

    better support people facing dementia alone.

    Eligibility Criteria

    You are eligible to participate if you:

    - Live in Ontario or Alberta AND

    - Have a diagnosis of dementia or are at-risk and planning for a future living with dementia and are

    facing dementia alone OR

    - Are a healthcare or social service worker, or other professional who has experience trying to connect

    adult clients with a substitute decision-maker OR

    - Have experience as a substitute decision-maker for someone living with dementia who is not a close

    family member or friend

    In addition, to be eligible you must:

    - Be able to participate in an interview over the phone, on Zoom, or in-person AND

    - Understand the purpose of the study and what participation involves

    -Speak English

    Recruitment End Date

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  • Observational Study
    In-Person and Online

    VRx@Home: A virtual reality at-home intervention for persons living with dementia and their care partners

    What is this Study about?

    VRx@Home is a 5-week virtual reality at-home intervention with the goal to explore whether virtual reality experiences can enhance communication between persons living with dementia and their care partners. We also aim to explore how a head-mounted VR system, which delivers a fully immersive experience compares to a Tablet-based technology.

    Eligibility Criteria

    • Persons living with mild-to-moderate dementia who are living at home
    • Person living with dementia has no history of stroke, bypass surgery, or seizure disorders
    • A friend/family care partner who speaks and understands English and is willing to also participate in the intervention
    • Resides in Greater Toronto Area (Toronto, Peel, Halton, York, and Durham regions)
    • Individuals who speak English

    Recruitment End Date

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  • Observational Study
    Elisabeth Bruyère Hospital 43 Bruyère Street Ottawa, ON

    Precision Microbiome Nutrition to Improve Brain Health

    What is this Study about?

    The study is aiming to assess whether nutritional intervention with personalized, preselected prebiotics can affect cognitive function in those with Alzheimer’s disease. This study is placebo-controlled, and participants will be randomized to either the placebo or prebiotic.

    Eligibility Criteria

    • Aged 60 or older
    • Diagnosis of Mild Cognitive Impairment, Alzheimer’s disease, or Amnestic Mild Cognitive Impairment
    • Has someone who can be their study partner

    Recruitment End Date

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  • Observational Study
    In-Person

    SCREEN: Measuring nutrition risk in community-living seniors

    What is this Study about?

    We want to determine if a nutrition questionnaire (SCREEN) works well to identify nutrition challenges for older adults with diagnosed memory problems, cognitive impairment or dementia when completed by themselves, or by a care partner on behalf of their cared for person.

    Eligibility Criteria

    You may be eligible if you are:

    • 55 years or older

    • Read/speak English

    • Live within 45km of Waterloo, Guelph or London.

    AND are an:

    • Older adult with diagnosed memory problems, cognitive impairment or dementia with a care partner who either lives with you, or who is in daily contact with you and would be able to support reporting of their eating behaviours

    • If living in a retirement home, the older adult must have lived in their home for at least 3 months and receive 2 or more meals each day from their retirement home

    Recruitment End Date

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  • Clinical Trial
    Alberta, British Columbia & Ontario

    A Trial of the Safety, Tolerability, and Pharmacodynamics of CVL-871 in Subjects With Dementia-Related Apathy

    What is this Study about?

    The purpose of this phase 2 study is to determine whether CVL-871 is safe and tolerable in patients with Dementia-Related Apathy and if CVL-871 shows changes in clinical measurements of apathy. 

    Eligibility Criteria

    • 50-85 years old
    • Diagnosis of apathy
    • Diagnosis of mild to moderate dementia related to Alzheimer's disease, Frontotemporal dementia, Vascular dementia or Lewy Body Disease dementia).

    Recruitment End Date

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  • Observational Study
    Canada-Wide (all provinces)

    Evolution of visuospatial abilities in adults with mild cognitive impairment: a longitudinal study

    What is this Study about?

    The aim is to better understand the cognitive strengths and difficulties related to visuospatial skills among people with Mild Cognitive Impairment and/or early Alzheimer's Disease through cognitive tasks.

    Eligibility Criteria

    • Adults with MCI and/or AD
      OR
    • Healthy, 40+ Years, with parent diagnosed with AD

    Recruitment End Date

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