
The Alzheimer Society Research Portal connects researchers with Canadians looking to participate in research studies. On this website, find active studies that you can participate in to help advance research on dementia.
The purpose of this study is to determine the effectiveness of DataDay, a digital self-management application, in improving the quality of life of patients and caregivers. In this respect, we aim to identify the benefits and challenges to the app’s usability and impact on health outcomes and quality of life for these individuals.
The information gathered from this study concerning the impact on patient and caregiver quality of life, as well as the feasibility and usability of the app will inform future iterations of the app.
– Are 18 years of age
– Are diagnosed with dementia (any type) or MCI (Patients can have moderate dementia insofar that they can understand and provide informed consent)
– Have the capacity to consent independently
– Are a caregiver: Must be caring for a person living with mild to moderate dementia or MCI
Please note: Access to a smartphone or tablet is not a requirement for participation. Participants may use their own device if they wish or can be supplied a tablet for the duration of the study. Access to Wi-Fi is not required.
‘Bootle Blast’ combines therapy and video games. It has been used with children and youth with musculoskeletal disabilities in clinics and homes. Preliminary research supports Bootle Blast’s ability to engage players and support physical outcomes. Informal testing suggests it may also appeal to older adults. This study will test Bootle Blast’s feasibility with people with dementia. Pairs of people with dementia and their caregivers (n=10) will play Bootle Blast at home for 2 weeks. Data will include video recordings, surveys, balance tests, safety and adherence tracking, and interviews. This study aims to inform a more accessible version of Bootle Blast.
People with Dementia
• Live in Ontario, Canada (within a two-hour drive from Toronto, Ontario)
• Speak and understand English
• Agree to be video and audio recorded as part of the study
• Be able to stand and walk, with or without an assistive device (e.g., a walker)
• Have the capacity to provide independent, informed consent
Caregivers
• Live in Ontario, Canada (within a two-hour drive from Toronto, Ontario)
• Speak and understand English
• Agree to be video and audio recorded as part of the study
This study consists of a 45-60 minutes virtual interview to better understand the experiences of familial caregivers of persons with dementia.
- Are 18 years of age or older
- Have been a part-time or full-time caregiver of a family member with dementia
- Speaks English
This study looks at how an at-home nature-based virtual reality (VR) program may help people living with Alzheimer’s disease manage behavioural and psychological symptoms of dementia (BPSD), such as depression. Caregivers/study partners will have the option of taking part in the study and providing feedback regarding the VR intervention. This project will explore how VR can be used as a non-pharmacological approach to prolong aging in place for individuals with BPSD, as BPSD contributes to rates of institutionalization. This will take place completely remotely, in your own home.
AD-D Participant Inclusion Criteria:
1) Clinical diagnosis of mild to early-moderate stage AD (including mixed dementia with AD) using the Diagnostic and Statistical Manual of Mental Disorders, 5th Ed. Criteria (29)
2) Age of 50 years or older
3) Medical stability to participate in the trial
4) Patient Health Questionnaire score 5-14
5) Investigator judgement on whether the participant is comfortable with technology
6) Access to WiFi and a smart device for connecting on WebEx and downloading the Fitbit and Muse applications
7) Have someone available to be present during all sessions
Caregiver Inclusion Criteria:
1) 18 years of age or older
2) Available to be present for all sessions
3) Ability to provide consent
4) Access to a smart device
Caregiver Exclusion Criteria:
1) Under 18 years of age
In collaboration with our South Asian community collaborators, our goal is to gain an in-depth understanding of new immigrant, multigenerational, South Asian family caregiving for a relative with dementia amidst COVID-19. The goal is to inform future family-centered, healthcare interventions aimed at supporting equity deserving families during times of crisis.
To achieve our goal, we are starting to recruit family care partners living in a multigenerational home and caring for a relative with dementia from each of the four groups of South Asian families. We will be using a multiple case study to examine new immigrant, multigenerational caregiving for a relative with dementia from the perspective of four groups of South Asian families; 1) Pakistani, 2) Bangladeshi, 3) Indian, and 4) Sri Lankan. We will also be using secondary data sources, including genograms, ecoMaps, and key documents.
We will be conducting interviews with a family care partners from each of the four groups. Following these interviews, we will hold four focus groups with a new purposeful sample of South Asian multigenerational care partners to understand if the findings from the interviews reflect their caregiving experiences thereby increasing the reliability of the study findings.
You are eligible if
1. You are caring for a family member or relative with memory loss or dementia
2. You are living in a multigenerational South Asian Family
3. You Identify with any of these four South Asian Countries: India, Pakistan, Bangladesh and Sri Lanka
4. You live in the Greater Toronto Area (GTA)
We are interested in how the brain changes in aging and with dementia. With this study, we will investigate how the brain senses and interprets sights and sounds. We are particularly interested in how listening to music, especially familiar music, evokes emotions and activates vivid memories. Learning how the brain processes music will help us understand why music therapy is such an effective tool for those with Alzheimer’s. We also aim to understand how the brain combines sights and sounds. This is an important part of how we navigate complex everyday situations, such as walking down a busy street. Alzheimer’s disease interferes with the brain’s ability to combine information from different senses, which could cause challenges in daily living.
You are eligible to participate in this study if you are:
You will not be eligible to participate in the study if you:
CAN-PROTECT is a Canada-wide online study recruiting participants and caregivers of persons with dementia to explore how lifestyle, background, and caretaking factors affect our health, quality of life, cognition, behaviour, and function as we age. CAN-PROTECT data will be analyzed and jointly published by the University of Calgary in partnership with the University of Exeter.
- Age 18 years or older
- Reside in Canada
- Have access to a computer/touchscreen device
- Can provide informed consent
- Do not have a diagnosis of dementia
- Additionally, we are enrolling participants who have previously or currently care for persons with dementia for caregiver-specific assessments
- Ability to speak English
Our study titled "Investigating the Role of Quantitative Susceptibility Mapping and Oxygen Extraction Fraction as Advanced Neuroimaging Biomarkers in Alzheimer's Disease" aims to develop non-invasive diagnostic biomarkers for Alzheimer's Disease (AD). We focus on evaluating the potential of QSM and OEF to differentiate between AD, Mild Cognitive Impairment (MCI), and Cognitively Unimpaired populations and to predict amyloid and tau pathology, using a Systems Biology approach. Leveraging the McGill University's TRIAD cohort, the study utilizes advanced imaging and machine learning to predict amyloid and tau presence, which could transform AD diagnostics and treatment. Methodologically, it involves preprocessing neuroimaging data and employing machine learning classifiers to analyze these features. The anticipated outcomes include validating QSM and OEF as non-invasive biomarkers for AD, establishing their correlation with amyloid and tau proteins, and developing predictive models for clinical decision-making, potentially resulting in significant advancements in AD diagnostics.
Are a member of the TRIAD cohort at McGill University, falling within one of the following categories: young control, cognitively unimpaired, mild cognitive impairment, or Alzheimer's Disease.
Are willing and able to undergo advanced neuroimaging techniques including MRI and PET without contraindications.
Have not had any significant neurological conditions (other than AD for the AD group) that might interfere with the results of the study.
Have no metal implants, devices, or other conditions that may contraindicate or distort MRI imaging.
Are not currently participating in other clinical trials or studies that involve interventions which might interfere with the results of this study.
Are able and willing to provide informed consent for participation in the study or have a legally authorized representative who can do so.
Do not have a history of substance abuse or other conditions that might confound the imaging and cognitive data.
Have not undergone any significant head trauma or surgery in the past 6 months.
Are not pregnant or planning to become pregnant during the duration of the study.
Are willing to comply with all study-related procedures, imaging sessions, and follow-up evaluations.
Ability to speak English and French
Caregivers of people living with dementia have direct experience of how the dementia is progressing. They are essential in evaluating the real-world benefits of treatment and making decisions to keep the person at home or consider different levels of care. The aim of this study is to develop a new CAregiver REported and weighted Dementia outcome measure (CARED).
You are eligible to participate if you are:
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