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  • Observational Study
    Online

    Aging Exceptionally Well: Identifying and Characterizing SuperAgers in the Canadian Longitudinal Study on Aging

    What is this Study about?

    We are identifying SuperAgers - older adults with memory as good as young adults - in the CLSA and evaluating the relationships between modifiable factors and SuperAger status. The study consists of a two-minute intake survey, followed by a 10-minute scheduled phone call on a later date, where we will conduct a series of memory related tasks.

    Eligibility Criteria

    We will be accepting individuals between the age of 20-45 who speak English 

    Recruitment End Date

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  • Observational Study
    Online

    Experiences of Familial Caregivers: The development of a new scale for compassion fatigue

    What is this Study about?

    The aim of this study is to develop a new psychological questionnaire that measures compassion fatigue – emotional and physical exhaustion that involves a decreased ability to experience empathy and compassion for others – and captures experiences unique to individuals acting as care partners for their family members who suffer from dementia. The results of this study will be disseminated through scientific publications and conference presentations.

    Eligibility Criteria

    You are eligible to participate if you:
    • Are older than 18 years old
    • Are a part- or full-time caregiver for a family member diagnosed with dementia
    • Speak English

    Recruitment End Date

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  • Observational Study
    Online

    Mobile/Tablet Validation of the Cogniciti Brain Health Assessment

    What is this Study about?

    This study measures how well an online assessment measures brain health on mobile devices. The assessment includes different memory and attention tasks completed on a mobile device or tablet. We are also looking for volunteers for a one-session study to support the development of the desktop version of the Brain Health Assessment.

    Eligibility Criteria

    • Are between the ages of 20–35, 50–65, or 80–95
    • Are fluent in English
    • Have no significant concerns about memory, and have no mild cognitive impairment, vascular dementia, Huntington’s disease, Alzheimer’s disease, any cancer treated with chemotherapy, brain tumour, Parkinson’s disease, schizophrenia, or current depression
    • Have access to a mobile/tablet and/or a computer
    • Are comfortable using a mobile/tablet and/or a computer and have internet access
    • Have not completed Cogniciti’s Brain Health Assessment in the past 6 months

    Recruitment End Date

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  • Observational Study
    Online

    Real men (care): Examination of Perceptions of Informal Care among male caregivers (RMC)

    What is this Study about?

    This study explores men’s thoughts and beliefs about unpaid caregiving for older adults in Canada in a 25-minute online survey. The findings will improve our understanding of men in Canadian society. This will help us to improve support and education opportunities for individuals with family members with long-term care needs.

    Eligibility Criteria

    You are eligible to participate if you:
    - Identify as a man
    - Have and support a family member with long-term physical or mental ill health issues, disability, or problems related to old age
    - Are 18 years of age or older
    - Speak English

    Recruitment End Date

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  • Observational Study
    Online

    Identifying Early Cognitive Decline Across the Dementia Continuum Using a Remote Digital Screener

    What is this Study about?

    This study evaluates an at-home, digital cognitive screening tool for older adults experiencing memory changes across the dementia continuum. Participants will complete a brief series of engaging, online brain games and surveys to determine the tool's accuracy compared to traditional clinical assessments. The goal of this study is to provide accessible, patient-friendly monitoring of brain health that reduces the need for clinic travel and lowers barriers to early detection of dementia.

    Eligibility Criteria

    You are eligible to participate if you:

    Are 50 years of age or older

    Either have healthy cognition or are experiencing noticeable memory or thinking changes (Subjective Cognitive Decline), or have a clinical diagnosis of Mild Cognitive Impairment (MCI) or dementia.

    Have access to a computer, laptop, or tablet with a reliable internet connection.

    Are able to provide informed consent, or have a legally authorized Substitute Decision Maker (SDM) who can provide consent on your behalf.

    Have adequate vision and motor skills to view a screen and tap or click to respond to prompts (such as a choice reaction time task), using glasses or standard aids if necessary.

    Are able to read and communicate in English.

    Do not have comorbid psychiatric conditions that interfere with cognitive function Do not have a history of brain injury or neurodevelopmental disorders

    Recruitment End Date

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  • Clinical Trial
    In-Person

    Master Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies as Assessed by Biomarker Status and Cognition

    What is this Study about?

    This study is a pre-screening process used to assess participants' potential eligibility for Roche interventional Alzheimer's disease studies.

    Eligibility Criteria

    Male or female participants aged 50 years of age to 90.
    Report of objective or subjective memory concerns (by the participant and/or their informant) within the last year with or without a previous clinical diagnosis of MCI or dementia due to AD.

    Recruitment End Date

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  • Clinical Trial
    In-Person

    A Randomized, Placebo-controlled, Parallel Group, 72-week Study to Evaluate the Efficacy and Safety of VHB937 in Participants With Early Alzheimer's Disease Followed by an Extension

    What is this Study about?

    The purpose of this study is to find out whether treatment with VHB937 is safe and beneficial in people with early Alzheimer's disease. The study will evaluate the safety of VHB937, as well as its effects on memory and other thinking abilities, on daily activities, and on changes in the brain. The study will also observe and measure how VHB937 is processed by the body and how the body responds to it.
    Official Title

    Eligibility Criteria

    Male or female participants aged 50 years of age to 85.
    Must have a study partner
    Diagnosis of Mild Cognitive Impairment (MCI) due to AD or mild AD

    Recruitment End Date

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  • Observational Study
    Online

    Exploring Resilience in Informal Caregivers of People Living with Dementia

    What is this Study about?

    This research study focuses on resilience, defined as a trajectory in which an individual can not only adapt but enhance and grow in challenging circumstances. This research aims to: 1) explore resilience-related behaviours in the context of informal Plwd caregiving by examining which behaviours are related to resiliency and how these behaviours are meaningful to caregivers and 2) determine the role of environmental and individual factors in resiliency of caregivers of Plwd. I gave begun the first part of this study, will involved forming a caregiver research partner team to help to identify potential behaviours, characteristics and resources that promote resiliency in caregivers. They have worked with me in further developing research questions and methodology for a large-scale survey study, which I am recruiting for now. Choice of survey measures will be guided by both previous literature and research partner input. This research also includes a cognitive component in order to ascertain the role of cognitive abilities in resiliency. The results of this research will assist in determining the most appropriate social and community supports for caregivers of Plwd and the individual, cognitive, psychological, and social factors that need to be considered when determining suitability between specific supports and individual caregivers. Improving supports for caregivers will improve both caregiver and PlwD health and well-being, and allow Plwd to live at home for longer.

    Eligibility Criteria

    - You are currently an unpaid caregiver for someone living with dementia in Canada

    - You have been in this caregiving role for at least 1 year

    - The person you care for may live with you, in their own home or in long-term care

    - You must be able to complete an online questionnaire in English

    - You have access to an internet connection and device

    Recruitment End Date

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  • Observational Study
    Online

    Effects of a Single-Session Online Therapy Program for Family and Friends of Long-Term Care Residents

    What is this Study about?

    This study explores the experiences of family and friends of long-term care residents. It focuses on how they experience stress, burden, and mental health challenges, and how a single-session online Acceptance and Commitment Therapy (ACT) or educational materials may help. We will use the information gathered from questionnaires and interventions to understand the effectiveness of these supports and to develop recommendations for improving resources, strategies, and interventions to better meet the needs of family and friends, helping them manage stress and maintain wellbeing while caring for someone in long-term care.

    Eligibility Criteria

    You are eligible to participate if you:

    - are at least 18 years old

    - currently reside in Canada

    - have a family member or friend who currently lives in long-term care

    - are not currently receiving psychological treatment

    Recruitment End Date

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