The Alzheimer Society Research Portal connects researchers with Canadians looking to participate in research studies. On this website, find active studies that you can participate in to help advance research on dementia.
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Selecting one or more of the options below will update the content below.
- Observational StudyIn-Person & Online
What is this Study about?
Dementia Friendly Communities is a community-based action research study that will engage directly with people with dementia who live independently. The goal of this study is to develop an in-depth understanding of the community-related needs of people with dementia who live independently, and to explain and demonstrate how communities can be dementia friendly, and support social inclusion and wellbeing.
Eligibility Criteria
You are eligible to participate if you:
- identify as someone living with dementia or memory impairment
- live independently in the community setting (ie: alone in your own home)
- can communicate in English
- are able and willing to participate as a member of the Action Group.
Recruitment End Date
- Observational StudyOnline
What is this Study about?
CAN-PROTECT is a Canada-wide online study recruiting participants and caregivers of persons with dementia to explore how lifestyle, background, and caretaking factors affect our health, quality of life, cognition, behaviour, and function as we age. CAN-PROTECT data will be analyzed and jointly published by the University of Calgary in partnership with the University of Exeter.
Eligibility Criteria
- Age 18 years or older
- Reside in Canada
- Have access to a computer/touchscreen device
- Can provide informed consent
- Do not have a diagnosis of dementia
- Additionally, we are enrolling participants who have previously or currently care for persons with dementia for caregiver-specific assessments
- Ability to speak English
Recruitment End Date
- Observational StudyOnline & In-Person
What is this Study about?
A dementia diagnosis impacts the cognitive, functional, and physical abilities of those diagnosed, which will influence their ability to perform activities of daily living including meal preparation and eating. Persons living with dementia can experience a range of difficulties while eating that will impact their ability to consume adequate food and fluids, which include but are not limited to swallowing, chewing, and self-feeding difficulties. Consequently, persons living with dementia are at increased risk of malnutrition and negative health outcomes. The objective of this study is to understand the experience of persons’ living with dementia or diagnosed memory problems and/or their caregivers in managing eating challenges and swallowing problems in the community.
Eligibility Criteria
You are eligible to participate if you:
- Speak English
- A person with memory problems experiencing eating challenges or swallowing problems in the community
- OR if you are or were a caregiver to a person with memory problems with eating challenges or swallowing problems.Recruitment End Date
- Clinical TrialIn-Person
What is this Study about?
The aim of this study is to assess the efficacy and safety of GSK4527226 in participants with early Alzheimer's Disease (AD) (including mild cognitive impairment [MCI] and mild dementia due to AD) of 2 dose levels of GSK4527226 compared to placebo.
Eligibility Criteria
Age 50 - 85
Mild cognitive impairment (MCI) or mild dementia due to Alzheimer's disease
Must have a study partnerRecruitment End Date
- Clinical TrialOnline
What is this Study about?
The goal of the proposed SYNERGIC-2 TRIAL (SYNchronizing Exercises, and Remedies to GaIn Cognition@home) is to evaluate cognitive improvements from personalized multidomain interventions that target multiple dementia risk factors delivered at home to older adults with Mild Cognitive Impairment (MCI).
Eligibility Criteria
- Aged 60-85 years.
- Concerned about memory or thinking problems.
- Have access to internet at home.
- Ability to speak English.
Recruitment End Date
- Observational StudyIn-Person
What is this Study about?
Our study titled "Investigating the Role of Quantitative Susceptibility Mapping and Oxygen Extraction Fraction as Advanced Neuroimaging Biomarkers in Alzheimer's Disease" aims to develop non-invasive diagnostic biomarkers for Alzheimer's Disease (AD). We focus on evaluating the potential of QSM and OEF to differentiate between AD, Mild Cognitive Impairment (MCI), and Cognitively Unimpaired populations and to predict amyloid and tau pathology, using a Systems Biology approach. Leveraging the McGill University's TRIAD cohort, the study utilizes advanced imaging and machine learning to predict amyloid and tau presence, which could transform AD diagnostics and treatment. Methodologically, it involves preprocessing neuroimaging data and employing machine learning classifiers to analyze these features. The anticipated outcomes include validating QSM and OEF as non-invasive biomarkers for AD, establishing their correlation with amyloid and tau proteins, and developing predictive models for clinical decision-making, potentially resulting in significant advancements in AD diagnostics.
Eligibility Criteria
Are a member of the TRIAD cohort at McGill University, falling within one of the following categories: young control, cognitively unimpaired, mild cognitive impairment, or Alzheimer's Disease.
Are willing and able to undergo advanced neuroimaging techniques including MRI and PET without contraindications.
Have not had any significant neurological conditions (other than AD for the AD group) that might interfere with the results of the study.
Have no metal implants, devices, or other conditions that may contraindicate or distort MRI imaging.
Are not currently participating in other clinical trials or studies that involve interventions which might interfere with the results of this study.
Are able and willing to provide informed consent for participation in the study or have a legally authorized representative who can do so.
Do not have a history of substance abuse or other conditions that might confound the imaging and cognitive data.
Have not undergone any significant head trauma or surgery in the past 6 months.
Are not pregnant or planning to become pregnant during the duration of the study.
Are willing to comply with all study-related procedures, imaging sessions, and follow-up evaluations.
Ability to speak English and French
Recruitment End Date
- Clinical TrialIn-Person
What is this Study about?
This Phase 2 study aims to study to evaluate the efficacy and safety of study treatment in paticipants with Mild Cognitive Impairment Due to Alzheimer's Disease or Mild Alzheimer's Disease Dementia
Eligibility Criteria
Age 50 - 80
Mild cognitive impairment (MCI) or mild dementia due to Alzheimer's diseaseRecruitment End Date
- Observational StudyIn-Person
What is this Study about?
Increasing evidence shows that listening to music from childhood and early adulthood can help recall meaningful events from the past. Importantly, people with dementia have shown to benefit from listening to personally meaningful music, suggesting that musical memory remains preserved. However, the underlying mechanisms by which music improves memory remains unclear.
My research addresses the impact of an autobiographically salient music listening program on memory and brain activity in mild cognitive impairment. Understanding how brainwave activity in this population may differ, will help elucidate mechanisms of music listening that lead to cognitive improvements, ultimately providing insight into musical memory preservation and how it can be leveraged.
Participants will undergo cognitive testing and measure brainwave activity via EEG, a non-invasive neuroimaging method. Participants will be provided an online link (or CD if they do not have wifi) to access their personalized music playlist and will be asked to listen for two weeks at home (20 mins/day, minimum 5 days/wk). Repeated cognitive and EEG assessment will help determine changes in brain function.
Eligibility Criteria
- are 60 years of age and over
- have received a diagnosis of mild cognitive impairment
- are English speaking
- have a minimum of high school education
- have adequate hearing and vision
- can identify 15 English vocal/lyrical songs that are associated to your personal memories
- can commit to listening to your personal playlist (20 mins) at-home for 2 weeks (minimum 5 days/week)
Recruitment End Date
- Observational StudyOnline & In-Person
What is this Study about?
This study, "Stranger than Family: Decision-Making & Ethics of Substitution for People Living With
Dementia Going It Alone", explores how people facing dementia alone are connected with a substitute
decision-maker and how ideas about capacity, consent, and decision-making affect them.
Interviews will be conducted with:
- People who are facing dementia alone
- Healthcare and social service workers
- Substitute decision-makers for others who are not close family members or close friends
The overall goal of this study is to identify opportunities for advocacy, policy, and practice change to
better support people facing dementia alone.
Eligibility Criteria
You are eligible to participate if you:
- Live in Ontario or Alberta AND
- Have a diagnosis of dementia or are at-risk and planning for a future living with dementia and are
facing dementia alone OR
- Are a healthcare or social service worker, or other professional who has experience trying to connect
adult clients with a substitute decision-maker OR
- Have experience as a substitute decision-maker for someone living with dementia who is not a close
family member or friend
In addition, to be eligible you must:
- Be able to participate in an interview over the phone, on Zoom, or in-person AND
- Understand the purpose of the study and what participation involves
-Speak English
Recruitment End Date
Alzheimer Society of Canada
20 Eglinton Avenue West, 16th Floor
Toronto, Ontario M4R 1K8
Information and Referral Line: 1-855-705-4636
Email: [email protected]
Charity registration number: 11878 4925 RR0001
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