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  • Clinical Trial
    Online

    Feasibility Testing a Youth Therapeutic Exercise Video Game System (‘Bootle Blast’) with People with Dementia

    What is this Study about?

    ‘Bootle Blast’ combines therapy and video games. It has been used with children and youth with musculoskeletal disabilities in clinics and homes. Preliminary research supports Bootle Blast’s ability to engage players and support physical outcomes. Informal testing suggests it may also appeal to older adults. This study will test Bootle Blast’s feasibility with people with dementia. Pairs of people with dementia and their caregivers (n=10) will play Bootle Blast at home for 2 weeks. Data will include video recordings, surveys, balance tests, safety and adherence tracking, and interviews. This study aims to inform a more accessible version of Bootle Blast.

    Eligibility Criteria

    People with Dementia
    • Live in Ontario, Canada (within a two-hour drive from Toronto, Ontario)
    • Speak and understand English
    • Agree to be video and audio recorded as part of the study
    • Be able to stand and walk, with or without an assistive device (e.g., a walker)
    • Have the capacity to provide independent, informed consent


    Caregivers
    • Live in Ontario, Canada (within a two-hour drive from Toronto, Ontario)
    • Speak and understand English
    • Agree to be video and audio recorded as part of the study

    Recruitment End Date

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  • Observational Study
    Online

    Exploring the Role of OHTs caring for Individuals living with Dementia and Their Caregivers

    What is this Study about?

    By understanding the perspectives of various stakeholders involved in dementia care within Ontario health teams, we aim to enhance the quality of life for individuals living with dementia in Ontario.

    Eligibility Criteria

    You are eligible to participate if you or your loved one is living with dementia and would like to share your experience so that we can act to improve the quality of care for individuals living with dementia in Ontario.

    Recruitment End Date

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  • Observational Study
    Online & In-Person

    Sensory Processing in Aging and Neurodegenerative Disease

    What is this Study about?

    We are interested in how the brain changes in aging and with dementia. With this study, we will investigate how the brain senses and interprets sights and sounds. We are particularly interested in how listening to music, especially familiar music, evokes emotions and activates vivid memories. Learning how the brain processes music will help us understand why music therapy is such an effective tool for those with Alzheimer’s. We also aim to understand how the brain combines sights and sounds. This is an important part of how we navigate complex everyday situations, such as walking down a busy street. Alzheimer’s disease interferes with the brain’s ability to combine information from different senses, which could cause challenges in daily living.

    Eligibility Criteria

    You are eligible to participate in this study if you are:

    • A healthy young adult aged 18-35, a healthy older adult aged 65 and up, or an older adult with mild/early-stage dementia as diagnosed by your doctor
    • Able to provide written, informed consent to participate
    • Have normal or corrected-to-normal hearing in both ears and vision in both eyes
    • You must have no history of cerebro-vascular injury or accident (such as a stroke)
    • For adults without dementia, you must have no known neurological conditions and must not be taking any neuroactive drugs

    You will not be eligible to participate in the study if you:

    • Have metallic objects that cannot be removed for the MEG recording (such as permanent piercings and medical implants that are made from magnetic metals)
    • Are pregnant
    • Feel you cannot perform the audio-visual and/or music listening tasks

    Recruitment End Date

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  • Clinical Trial
    Ontario

    Accelerated intermittent theta burst stimulation to enhance cognitive function and balance in dementia

    What is this Study about?

    McMaster University, in partnership with Ressam Gardens Memory Care Community, is conducting a study on the effects of brain stimulation in individuals aged 50 and older with dementia or memory loss. The research focuses on using repetitive transcranial magnetic stimulation (rTMS), a non-invasive technique that delivers magnetic pulses to the brain, to enhance cognitive function and balance. The goal is to extend the positive effects of brain stimulation in improving cognition and balance in individuals with dementia.

    Eligibility Criteria

    You are eligible to participate if you…

    1.) Diagnosed with Dementia and/or memory loss by a clinician

    2.) Exhibit adequate oral communication skills and cognitive function sufficient to obtain a score ranging between 10-27 on the Mini-Mental State Exam

    3.) Walk or stand with or without personnel or assistive devices

    4.) Individuals must be greater than or equal to 50 years of age

    Recruitment End Date

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