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  • Observational Study
    Online

    Identifying Early Cognitive Decline Across the Dementia Continuum Using a Remote Digital Screener

    What is this Study about?

    This study evaluates an at-home, digital cognitive screening tool for older adults experiencing memory changes across the dementia continuum. Participants will complete a brief series of engaging, online brain games and surveys to determine the tool's accuracy compared to traditional clinical assessments. The goal of this study is to provide accessible, patient-friendly monitoring of brain health that reduces the need for clinic travel and lowers barriers to early detection of dementia.

    Eligibility Criteria

    You are eligible to participate if you:

    Are 50 years of age or older

    Either have healthy cognition or are experiencing noticeable memory or thinking changes (Subjective Cognitive Decline), or have a clinical diagnosis of Mild Cognitive Impairment (MCI) or dementia.

    Have access to a computer, laptop, or tablet with a reliable internet connection.

    Are able to provide informed consent, or have a legally authorized Substitute Decision Maker (SDM) who can provide consent on your behalf.

    Have adequate vision and motor skills to view a screen and tap or click to respond to prompts (such as a choice reaction time task), using glasses or standard aids if necessary.

    Are able to read and communicate in English.

    Do not have comorbid psychiatric conditions that interfere with cognitive function Do not have a history of brain injury or neurodevelopmental disorders

    Recruitment End Date

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  • Observational Study
    In-Person

    Accelerated intermittent theta burst stimulation to enhance cognitive function and balance in dementia

    What is this Study about?

    McMaster University is conducting a study on the effects of brain stimulation in individuals aged 50 and older with dementia or memory loss. The research focuses on using repetitive transcranial magnetic stimulation (rTMS), a noninvasive technique that delivers magnetic pulses to the brain, to enhance cognitive function and balance. The goal is to extend the positive effects of brain stimulation in improving cognition and balance in individuals with dementia.

    Eligibility Criteria

    1.) Diagnosed with Dementia and/or memory loss by a clinician

    2.) Exhibit adequate oral communication skills and cognitive function

    3.) Walk or stand with or without personnel or assistive devices

    4.) Individuals must be greater than or equal to 50 years of age

    Recruitment End Date

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  • Observational Study
    Online & In-Person

    Bridge2AI-Voice as a Biomarker of Health

    What is this Study about?

    The aim of this study is to develop a large, ethically sources, and diverse database of voice recordings to determine whether voice has biomarkers for particular disease categories, including neurological and neurodevelopmental conditions. The data that is collected will be used to develop a full open-access database to fuel artificial intelligence research related to voice.

    Eligibility Criteria

    • Between ages of 44-85
    • Able to read, write, speak, and understand English
    • Be diagnosed with one of the following conditions:
      • Alzheimer’s disease
      • Parkinson’s disease
      • Amyotrophic Lateral Sclerosis
      • Mild Cognitive Impairment, or other types of dementia
    • Consent to provide a voice/speech sample

    Recruitment End Date

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