What is this Study about?

The purpose of this study is to measure the difference in time to developing or worsening memory, thinking, or functional problems due to Alzheimer's disease occurring in participants receiving study drug compared to placebo.

Participation could last up to 255 weeks including screening, a double-blind treatment period, and a double-blind observation period. In addition, eligible participants who receive placebo during the double-blind treatment period may choose to extend their study participation to receive open-label remternetug in an extension period.

What is this Study about?

Qualitative study using semi-structure interviews to gain understanding of occupational transitions of caregivers during menopause to inform increased services to meet these needs.

What is this Study about?

The purpose of this study is to determine the effectiveness of DataDay, a digital self-management application, in improving the quality of life of patients and caregivers. In this respect, we aim to identify the benefits and challenges to the app’s usability and impact on health outcomes and quality of life for these individuals.

The information gathered from this study concerning the impact on patient and caregiver quality of life, as well as the feasibility and usability of the app will inform future iterations of the app.

What is this Study about?

The study involves a primary session of paper-and-pencil tasks, and a second session of a computer task, while your heart rate and brain activity is monitored. The aim of the study is to examine how signals are affected from the body to the brain.

What is this Study about?

Increasing evidence shows that listening to music from childhood and early adulthood can help recall meaningful events from the past. Importantly, people with dementia have shown to benefit from listening to personally meaningful music, suggesting that musical memory remains preserved. However, the underlying mechanisms by which music improves memory remains unclear.

My research addresses the impact of an autobiographically salient music listening program on memory and brain activity in mild cognitive impairment. Understanding how brainwave activity in this population may differ, will help elucidate mechanisms of music listening that lead to cognitive improvements, ultimately providing insight into musical memory preservation and how it can be leveraged.

Participants will undergo cognitive testing and measure brainwave activity via EEG, a non-invasive neuroimaging method. Participants will be provided an online link (or CD if they do not have wifi) to access their personalized music playlist and will be asked to listen for two weeks at home (20 mins/day, minimum 5 days/wk). Repeated cognitive and EEG assessment will help determine changes in brain function.

What is this Study about?

‘Bootle Blast’ combines therapy and video games. It has been used with children and youth with musculoskeletal disabilities in clinics and homes. Preliminary research supports Bootle Blast’s ability to engage players and support physical outcomes. Informal testing suggests it may also appeal to older adults. This study will test Bootle Blast’s feasibility with people with dementia. Pairs of people with dementia and their caregivers (n=10) will play Bootle Blast at home for 2 weeks. Data will include video recordings, surveys, balance tests, safety and adherence tracking, and interviews. This study aims to inform a more accessible version of Bootle Blast.

What is this Study about?

By understanding the perspectives of various stakeholders involved in dementia care within Ontario health teams, we aim to enhance the quality of life for individuals living with dementia in Ontario.

What is this Study about?

Scientific evidence indicates that healthy lifestyle habits promote brain health and help prevent Alzheimer’s disease.

Our study consists of evaluating a personalized program designed to promote healthy lifestyle habits with the goal of supporting brain health.

This program, called Luci, is available as an online platform with virtual guidance from an advisor. Its purpose is to help participants change their lifestyle habits. It focuses on three areas: physical activity, healthy eating, and intellectual stimulation.

The aim of this study is to determine whether our program helps improve lifestyle habits in these three areas, along with other indicators linked to brain health.

What is this Study about?

This study consists of a 45-60 minutes virtual interview to better understand the experiences of familial caregivers of persons with dementia.