Selecting one or more of the options below will update the content below.

Show / Hide Filters
Age Group
Type of Study
Study Format
Location
Target Population
  • Observational Study
    In-Person

    What is this Study about?

    McMaster University is conducting a study on the effects of brain stimulation in individuals aged 50 and older with dementia or memory loss. The research focuses on using repetitive transcranial magnetic stimulation (rTMS), a noninvasive technique that delivers magnetic pulses to the brain, to enhance cognitive function and balance. The goal is to extend the positive effects of brain stimulation in improving cognition and balance in individuals with dementia.

    Eligibility Criteria

    1.) Diagnosed with Dementia and/or memory loss by a clinician

    2.) Exhibit adequate oral communication skills and cognitive function

    3.) Walk or stand with or without personnel or assistive devices

    4.) Individuals must be greater than or equal to 50 years of age

    Recruitment End Date

  • Observational Study
    In-person & Online

    What is this Study about?

    Arksey and O’Malley’s framework for conducting scoping reviews includes a consultative exercise with people who have lived experiences related to the topic of the literature. Such consultations, in the case of this study being in the form of a focus group, help ensure the findings remain grounded in peoples’ everyday realities, and as such the results of the review are more useful for informing policy and practice. Moreover, focus group participants can share what gaps they identify in the literature based on their lived experiences, which can inform future research that better addresses their needs and circumstances. Therefore, after synthesizing the literature for each topic, we are host an approximately one-hour long focus group for people who have participated in exercise programs for people living with dementia (exercise leaders, carers, and people living with dementia) who will share their thoughts on the literature.

    Eligibility Criteria

    • Living with dementia, a family care partner of someone living with dementia, or a professional who works to support people living with dementia.

    • Able to read, write, and speak in English.

    Recruitment End Date

  • Observational Study
    In person & Online

    What is this Study about?

    This study explores how adult day programs affect the lives of people living with dementia and their caregivers across several Canadian regions. Over time, we gather information about health, well-being, daily experiences, and quality of life of people living with dementia who attend day program and their caregivers. We also aim to learn about day programs themselves, such as their activities, staffing, challenges, and successes. By combining surveys, interviews, and focus groups, our program of research aims to understand what makes day programs helpful, where challenges exist, and how day program can better support families, and people who use them.

    Eligibility Criteria

    You are eligible to participate if you:

    • Are an older adult living with dementia who attends or does not attend a day program

    • You are a family/friend caregiver of someone living with dementia who attends or does not attend a day program

    • Live in one of the participating regions (Ontario, Winnipeg MB, Calgary AB, or Interior BC)

    • Are able to take part in a conversation or complete surveys, with support if needed

    Recruitment End Date

  • Observational Study
    In-Person

    What is this Study about?

    Hearing loss is the third most common chronic health condition among people 65 and older and increases the risk of social isolation, depression, communication difficulties and dementia. Dementia risk may be reduced through hearing rehabilitation, and it is critical to develop tools for identifying hearing loss and its impact on communication. The Hearing and Functioning in Everyday Life Questionnaire (HFEQ) is a measure to identify hearing loss and everyday life functioning, not yet been evaluated for people with combined hearing loss and cognitive impairment. To bridge this gap, the aim is to evaluate the HFEQ for this group. The study has a cross-sectional observational study design. Adults over 60 years, with hearing loss and with and without cognitive impairment will be recruited. Data collection will include a cognitive and hearing assessment, assessment of conversation effectiveness and efficiency, hearing and general health history and five questionnaires (HFEQ, the Life-Space questionnaire, the Social Functioning in Dementia scale, and the PROMIS anxiety and depression scales).

    Eligibility Criteria

    • Are 60 years or older

    • Have hearing loss

    Experience cognitive complaints (subjective memory complaints, mild cognitive impairment, or dementia) or,

    • Experience no changes in cognitive function

    Recruitment End Date

  • Observational Study
    In person & Online

    What is this Study about?

    This study will assess if an in-vehicle Driving Monitoring System can identify differences in driving behaviours between older adults who are cognitively healthy, those with mild cognitive impairment, and those with mild dementia. 

    Eligibility Criteria

    Participants must:

    • Be 65 years or older.

    • Be cognitively healthy or have mild cognitive impairment or mild dementia.

    • Have a valid General class driver’s license and still driving.

    • Be fluent in English.

    • Own an insured vehicle of 1998 or newer model year.

    • Drive to at least 2 different locations per week. 

    Recruitment End Date

  • Observational Study
    In person

    What is this Study about?

    This study explores Deep Brain Stimulation (DBS) as a potential treatment for mild Alzheimer’s disease (AD). In this study, the mild electrical stimulation is delivered to a part of the brain called the Pedunculopontine Nucleus (PPN), which helps regulate cognitive and sleep-related brain rhythms. The trial will recruit a small group of participants to evaluate the safety, feasibility, and preliminary efficacy of DBS-PPN in treating AD. The goal of this study is to see if targeting this part of the brain with DBS can help people living with mild AD improve their memory, thinking skills, and sleep quality.

    Eligibility Criteria

    Are 60 years or older
    -Have a diagnosis of mild Alzheimer's Disease
    -Are fluent in English
    -Have a personal caregiver willing to join the study

    Recruitment End Date

  • Observational Study
    In person and online

    What is this Study about?

    This study aims to evaluate the acceptance and usability of the GuardIO Family Care app, a mobile application designed to support community safety for individuals living with dementia or mild cognitive impairment and their care partners. The study also aims to analyze mobility patterns collected from the app to explore how mobility data can contribute to the early detection of cognitive impairment. The findings will help improve app design, inform care strategies, and support early intervention efforts for individuals living with dementia or MCI.

    Eligibility Criteria

    You are eligible to participate if you:

    Are 18 years of age or older

    Are living with mild cognitive impairment (MCI) or dementia, or are a care partner of someone with MCI or dementia

    Are able to use a smartphone or tablet with the GuardIO app

    Are willing to participate in the study activities, including using the app, completing questionnaires, and attending an optional focus group

    Can understand and communicate in English (or another supported language, if applicable)

    Recruitment End Date

  • Clinical Trial
    In-Person

    What is this Study about?

    We are conducting three separate studies to explore the effects of transcranial Direct Current Stimulation (tDCS) in individuals with Alzheimer’s Disease or Primary Progressive Aphasia. tDCS is a non-invasive therapy that uses low electrical currents to stimulate specific areas of the brain. Previous research has suggested that tDCS can improve symptoms such as language difficulties and may help slow the progression of Alzheimer’s.

    Our studies aim to investigate these effects in different contexts, including language therapy and overall mental abilities. Upon completion, participants will receive their study results to help guide their decisions about whether tDCS could be part of a long-term therapy plan.

    Eligibility Criteria

    Person living with Alzheimer's disease

    Recruitment End Date

  • Clinical Trial
    Online

    What is this Study about?

    The Communication Bridge 3 Study is focused on helping adults with mild to moderate Primary Progressive Aphasia (PPA), a condition that affects language abilities due to neurodegenerative diseases. The study aims to improve functional communication and life participation by providing structured language and communication support remotely through video conferencing.

    Participants work with speech-language pathologists to practice communication techniques and learn strategies to address daily communication challenges. The study involves a series of therapy sessions, assessments, and follow-up evaluations to measure changes in communication and participation over time. By tracking participants' progress, the study hopes to identify effective approaches for enhancing quality of life for those living with PPA and their care partners.

    Eligibility Criteria

    You are eligible to participate if you speak English as a primary language, a confirmed diagnosis of PPA in mild to moderate impairment stage, a communication partner that is willing to participate, and sufficient internet connection.

    Recruitment End Date