Eligibility Criteria

Male or female participants aged 50 years of age
Has a history of previous clinical intracerebral hemorrhage.
Has probable CAA.

Eligibility Criteria

Male or female participants aged 50 years of age to 90.
Report of objective or subjective memory concerns (by the participant and/or their informant) within the last year with or without a previous clinical diagnosis of MCI or dementia due to AD.

Eligibility Criteria

Male or female participants aged 50 years of age to 90.
Must have a study partner
Participant- and/or Informant-reported history of cognitive decline with gradual onset and progression over the last 1 year before screening

Eligibility Criteria

Male or female participants aged 50 years of age to 85.
Must have a study partner
Diagnosis of Mild Cognitive Impairment (MCI) due to AD or mild AD

Eligibility Criteria

To be eligible to participate in this study you must:

• be 60 years of age or older

• be living independently in the community

• have normal or corrected-to-normal vision and hearing

• read, write, and speak English fluently

• have feelings of memory decline in the past 5 years

• be able to exercise at a moderate pace for 60 minutes 3x/week receive clearance from a medical doctor (once deemed eligible) to participate in an exercise program

You are ineligible to participate in this study if you:

• cannot partake or commit to exercise training 3x/week for 26 weeks or have regularly engaged in exercise (more than once per week) over the past 3 months

• cannot partake or commit to consuming a daily supplement for 26 weeks or consumed nutritional supplements containing creatine monohydrate over the past 3 months

• have a known allergy to creatine monohydrate or dextrose (glucose, D-glucose)

• have been diagnosed with a neurological disorder (e.g., Alzheimer’s disease, Parkinson’s disease)

• have pre-existing kidney disease, heart disease, or liver abnormalities

• have one or more uncontrolled chronic or psychiatric conditions (e.g., hypertension, diabetes, depression, anxiety)

• are taking medication that may impact kidney function (e.g., non-steroidal anti-inflammatory drugs, such as ibuprofen and naproxen)

• are ineligible or uncomfortable with blood sampling.

Eligibility Criteria

1.) Diagnosed with Dementia and/or memory loss by a clinician

2.) Exhibit adequate oral communication skills and cognitive function

3.) Walk or stand with or without personnel or assistive devices

4.) Individuals must be greater than or equal to 50 years of age

Eligibility Criteria

- are between the ages 60-90

- have up to grade 12 education

- have an individual (spouse, friend, or relative), called a “study partner,” who is willing to:

- Accompany you to the study visits

- Communicate to the study staff of changes in your health status over the period of this study

Eligibility Criteria

You are eligible to participate if you:

• Are an older adult living with dementia who attends or does not attend a day program

• You are a family/friend caregiver of someone living with dementia who attends or does not attend a day program

• Live in one of the participating regions (Ontario, Winnipeg MB, Calgary AB, or Interior BC)

• Are able to take part in a conversation or complete surveys, with support if needed

Eligibility Criteria

• Are 60 years or older

• Have hearing loss

• Experience cognitive complaints (subjective memory complaints, mild cognitive impairment, or dementia) or,

• Experience no changes in cognitive function